DERMATOLOGY
Working with a dermatology expert from preclinical to proof of concept can help to speed up your development program. As one of our therapeutic specialties, Oneiric Internationals conducts specific safety assessments for locally acting dermatology therapies and proof of concept in locally or centrally acting therapies, including both small and large molecules.
We assess toxicology of topical therapies, including edema/erythema measurement and Draize scoring, using mini pigs or NHPs. In the clinic, we collaborate closely with our consulting dermatologists who perform specialized assessments, such as biopsies or scoring lesion severity. If your locally acting product requires irritation and sensitization studies, our dedicated clinic areas can offer different climates.
Types of Dermatology Trials:
- Drug Trials: Investigate the safety and efficacy of new medications for various skin conditions, such as acne, psoriasis, eczema, or skin cancers.
- Device Trials: Assess the effectiveness and safety of new medical devices used in dermatological procedures, such as lasers, light therapies, or cosmetic devices.
- Interventional Trials: Evaluate the impact of specific interventions, such as topical treatments, phototherapy, or surgical procedures, on dermatological health.
- Prevention Trials: Focus on strategies to prevent the development or recurrence of skin conditions, including studies on sun protection, lifestyle modifications, or immunizations.
Endpoints:
- Common endpoints in dermatology trials include improvements in skin appearance, reduction in symptoms (e.g., itching, redness), quality of life, and the prevention of disease recurrence.